Bronchiolitis laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Laboratory Findings Adapted from the AAP Diagnosis and Management of Bronchiolitis Guideline, 2006.[1]
Evidence have not shown benefit in the use of laboratory tests for the diagnosis of bronchiolitis or for the assessment of severity. Diagnosis of bronchiolitis and of the severe forms of the disease should be made based on clinical findings and risk factors.
Specific viral testing have not shown benefits as there won't be any changes in the management nor the prognosis of the disease if the specific pathogen is determined. However, some institutions use specific RSV tests to prevent nosoccomial spread of the disease.[2] Specific viral pathogen tests are available. Specific antigen based tests are more commonly used:[3]
- ELISA
- Direct immunofluorescent assays
- Indirect immunofluorescent assays
- Optical immunoassays
Testas are available for the following viruses:
The complete blood counts (CBC) vary in each child and have not shown benefits for the diagnosis of bronchiolitis.[3]
References
- ↑ American Academy of Pediatrics Subcommittee on Diagnosis and Management of Bronchiolitis (2006). "Diagnosis and management of bronchiolitis". Pediatrics. 118 (4): 1774–93. doi:10.1542/peds.2006-2223. PMID 17015575.
- ↑ Bordley WC, Viswanathan M, King VJ, Sutton SF, Jackman AM, Sterling L; et al. (2004). "Diagnosis and testing in bronchiolitis: a systematic review". Arch Pediatr Adolesc Med. 158 (2): 119–26. doi:10.1001/archpedi.158.2.119. PMID 14757603.
- ↑ 3.0 3.1 Mandell, Gerald L.; Bennett, John E. (John Eugene); Dolin, Raphael. (2010). Mandell, Douglas, and Bennett's principles and practice of infectious disease. Philadelphia, PA: Churchill Livingstone/Elsevier.