Sandbox/00030

Classification of Disease Severity

Severity	Definition
Mild	CDI with diarrhea as the only symptom.
Moderate	CDI with diarrhea but without additional symptoms/signs meeting the definition of severe or complicated CDI.
Severe	CDI that presents with or develops during the course of the disease with hypoalbuminemia (serum albumin < 3 g/dl) and either of the following: A white blood cell (WBC) count ≥15,000 cells/mm3 Abdominal tenderness without criteria of complicated disease
Complicated	CDI that presents with or develops at least one of the following signs or symptoms: Admission to intensive care unit Hypotension with or without required use of vasopressors Fever ≥38.5°C Ileus or significant abdominal distention Mental status changes WBC ≥35,000 cells/mm3 or <2,000 cells/ mm3 Serum lactate levels >2.2 mmol/l Any evidence of end organ failure