Allopurinol (oral)
Synonyms / Brand Names: Allopurinolum, Allopurinol Sodium, Alopurinol, 7HP, Adenock, Ailural, Allo-Puren, Allopur, Allozym, Allural, Aloprim, Aloral, Alositol, Aluline, Anoprolin, Anzief, Apo-Allopurinol, Apulonga, Apurin, Apurol, Atisuril, Bleminol, Bloxanth, Caplenal, Cellidrin, Cosuric, Dabrosin, Dabroson, Dura Al, Embarin, Epidropal, Epuric, Foligan, Geapur, Gichtex, Gotax, HPP, Hamarin, Hexanuret, Ketanrift, Ketobun-A, Ledopur, Lopurin, Lysuron, Milurit, Miniplanor, Monarch, Nektrohan, Progout, Purinol, Remid, Riball, Sigapurol, Suspendol, Takanarumin, Urbol, Uricemil, Uriprim, Uripurinol, Uritas, Urobenyl, Urolit, Urosin, Urtias, Urtias 100, Xanturat, Zyloprim, Zyloric, Allohexal
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
The dosage of Allopurinol to accomplish full control of gout and to lower serum uric acid to normal or near-normal levels varies with the severity of the disease. The average is 200 to 300 mg per day for patients with mild gout and 400 to 600 mg per day for those with moderately severe tophaceous gout. The appropriate dosage may be administered in divided doses or as a single equivalent dose with the 300 mg tablet. Dosage requirements in excess of 300 mg should be administered in divided doses. The minimal effective dosage is 100 to 200 mg daily and the maximal recommended dosage is 800 mg daily. To reduce the possibility of flare-up of acute gouty attacks, it is recommended that the patient start with a low dose of Allopurinol (100 mg daily) and increase at weekly intervals by 100 mg until a serum uric acid level of 6 mg/dL or less is attained but without exceeding the maximal recommended dosage.
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Pill Images
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Publication Resources
Most Recent Articles on Allopurinol (oral)
Review Articles on Allopurinol (oral)
Articles on Allopurinol (oral) in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Allopurinol (oral)
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Trial Resources
Ongoing Trials with Allopurinol (oral) at Clinical Trials.gov
Trial Results with Allopurinol (oral)
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Allopurinol (oral)
Cochrane Collaboration on Allopurinol (oral)
Cost Effectiveness of Allopurinol (oral)
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Media Resources
Powerpoint Slides on Allopurinol (oral)
Images of Allopurinol (oral)
Podcasts & MP3s on Allopurinol (oral)
Videos on Allopurinol (oral)
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Allopurinol (oral)
Discussion Groups on Allopurinol (oral)
Patient Handouts on Allopurinol (oral)
Blogs on Allopurinol (oral)
Allopurinol (oral) in the News
Allopurinol (oral) in the Marketplace
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International Resources
Allopurinol (oral) en Español
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Adapted from the FDA Package Insert.