Gitoformate
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| Clinical data | |
|---|---|
| ATC code | |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C46H64O19 |
| Molar mass | 920.989 g/mol |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Gitoformate (INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat).[1] Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.
Chemistry
Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar.[2][3] Gitoxin, a cardiac glycoside from the Woolly Foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside.[4]
References
- ↑ PMID 6541927 (PMID 6541927)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ PMID 6542412 (PMID 6542412)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand - ↑ Template:PubChem
- ↑ William O. Foye,Thomas L. Lemke, David A. Williams. Foye's principles of medicinal chemistry. p. 699. ISBN 978-0-7817-6879-5.
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- Cardiac glycosides
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