5'-3' exoribonuclease 1
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5'-3' exoribonuclease 1 | |
---|---|
Identifiers | |
Symbol | XRN1 |
Entrez | 54464 |
HUGO | 30654 |
OMIM | 607994 |
RefSeq | NM_019001 |
UniProt | Q8IZH2 |
Other data | |
Locus | Chr. 3 q23 |
5'-3' exoribonuclease 1 (XRN1) is an exoribonuclease enzyme encoded in humans by the XRN1 gene. This enzyme hydrolyses RNA in the 5’ to 3’ direction.[1]
References
- ↑ Mullen, T. E.; Marzluff, W. F. (1 January 2008). "Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'". Genes & Development. 22 (1): 50–65. doi:10.1101/gad.1622708. PMC 2151014. PMID 18172165.
External links
- XRN1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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