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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

The Grading scheme is used to indicate whether a therapy is recommended or not according to the balance among benefits, risks, burdens, and possibly cost, and the degree of confidence in estimates of benefits, risks, and burdens.[1]

Grading Scheme Classification

  • Grade 1: Strong recommendation
  • Grade 2: Weak recommendation

Level of Evidence

The level of evidence is classified according to the factors that include the study design, the consistency of the results, and the directness of the evidence.[1]

  • Grade A: High
  • Grade B: Moderate
  • Grade C: Low

Resources

Grading Strength of Recommendations and Quality of Evidence in Clinical Guidelines[1]

References

  1. 1.0 1.1 1.2 Guyatt G, Gutterman D, Baumann MH, Addrizzo-Harris D, Hylek EM, Phillips B; et al. (2006). "Grading strength of recommendations and quality of evidence in clinical guidelines: report from an american college of chest physicians task force". Chest. 129 (1): 174–81. doi:10.1378/chest.129.1.174. PMID 16424429.


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