AFM (gene)

Afamin
Identifiers
Symbols	AFM ; ALB2; ALBA; ALF; MGC125338; MGC125339
External IDs	Template:OMIM5 Template:MGI HomoloGene: 881
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Afamin, also known as AFM, is a human gene.

This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.

Further reading

• Noppe M, Lowenthal A, Karcher D, Gheuens J (1979). "A two-site immunoradiometric assay for the determination of alpha-albumin". J. Immunol. Methods. 27 (1): 75–81. PMID 37276.CS1 maint: Multiple names: authors list (link)
• Hansson E, Rönnbäck L, Lowenthal A, Noppe M (1985). "Primary cultures from defined brain areas; effects of seeding time on cell growth, astroglial content and protein synthesis". Brain Res. 353 (2): 175–85. PMID 4041902.CS1 maint: Multiple names: authors list (link)
• Lowenthal A, Flament-Durand J, Karcher D; et al. (1982). "Glial cells identified by anti-alpha-albumin (anti-GFA) in human pineal gland". J. Neurochem. 38 (3): 863–5. PMID 7035619.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lichenstein HS, Lyons DE, Wurfel MM; et al. (1994). "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family". J. Biol. Chem. 269 (27): 18149–54. PMID 7517938.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Allard D, Gilbert S, Lamontagne A; et al. (1995). "Identification of rat alpha-albumin and cDNA cloning of its human ortholog". Gene. 153 (2): 287–8. PMID 7875606.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nishio H, Heiskanen M, Palotie A; et al. (1996). "Tandem arrangement of the human serum albumin multigene family in the sub-centromeric region of 4q: evolution and chromosomal direction of transcription". J. Mol. Biol. 259 (1): 113–9. doi:10.1006/jmbi.1996.0306. PMID 8648639.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nishio H, Dugaiczyk A (1996). "Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family". Proc. Natl. Acad. Sci. U.S.A. 93 (15): 7557–61. PMID 8755513.
• Song YH, Naumova AK, Liebhaber SA, Cooke NE (1999). "Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster". Genome Res. 9 (6): 581–7. PMID 10400926.CS1 maint: Multiple names: authors list (link)
• Khan MA, Kumar Y, Tayyab S (2003). "Bilirubin binding properties of pigeon serum albumin and its comparison with human serum albumin". Int. J. Biol. Macromol. 30 (3–4): 171–8. PMID 12063119.CS1 maint: Multiple names: authors list (link)
• Voegele AF, Jerković L, Wellenzohn B; et al. (2003). "Characterization of the vitamin E-binding properties of human plasma afamin". Biochemistry. 41 (49): 14532–8. PMID 12463752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics. 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID 14760718.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jerkovic L, Voegele AF, Chwatal S; et al. (2005). "Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression". J. Proteome Res. 4 (3): 889–99. doi:10.1021/pr0500105. PMID 15952736.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hu Y, Malone JP, Fagan AM; et al. (2006). "Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid". Mol. Cell Proteomics. 4 (12): 2000–9. doi:10.1074/mcp.M500207-MCP200. PMID 16199891.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ramachandran P, Boontheung P, Xie Y; et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)