AP1GBP1

AP1 gamma subunit binding protein 1
Identifiers
Symbols	AP1GBP1 ; MGC104959; SYNG
External IDs	Template:OMIM5 Template:MGI HomoloGene: 50953
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

AP1 gamma subunit binding protein 1, also known as AP1GBP1, is a human gene.

This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Further reading

• Peyrard M, Parveneh S, Lagercrantz S; et al. (1998). "Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG)". Genomics. 50 (2): 275–80. doi:10.1006/geno.1998.5289. PMID 9653655.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Page LJ, Sowerby PJ, Lui WW, Robinson MS (1999). "Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin". J. Cell Biol. 146 (5): 993–1004. PMID 10477754.CS1 maint: Multiple names: authors list (link)
• Hirst J, Lui WW, Bright NA; et al. (2000). "A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome". J. Cell Biol. 149 (1): 67–80. PMID 10747088.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fernández-Chacón R, Achiriloaie M, Janz R; et al. (2000). "SCAMP1 function in endocytosis". J. Biol. Chem. 275 (17): 12752–6. PMID 10777571.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takatsu H, Yoshino K, Nakayama K (2000). "Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin". Biochem. Biophys. Res. Commun. 271 (3): 719–25. doi:10.1006/bbrc.2000.2700. PMID 10814529.CS1 maint: Multiple names: authors list (link)
• Nogi T, Shiba Y, Kawasaki M; et al. (2002). "Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain". Nat. Struct. Biol. 9 (7): 527–31. doi:10.1038/nsb808. PMID 12042876.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kent HM, McMahon HT, Evans PR; et al. (2003). "Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin". Structure. 10 (8): 1139–48. PMID 12176391.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mills IG, Praefcke GJ, Vallis Y; et al. (2003). "EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking". J. Cell Biol. 160 (2): 213–22. doi:10.1083/jcb.200208023. PMID 12538641.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lui WW, Collins BM, Hirst J; et al. (2004). "Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin". Mol. Biol. Cell. 14 (6): 2385–98. doi:10.1091/mbc.E02-11-0735. PMID 12808037.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hirst J, Borner GH, Harbour M, Robinson MS (2005). "The aftiphilin/p200/gamma-synergin complex". Mol. Biol. Cell. 16 (5): 2554–65. doi:10.1091/mbc.E04-12-1077. PMID 15758025.CS1 maint: Multiple names: authors list (link)
• Theos AC, Tenza D, Martina JA; et al. (2006). "Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes". Mol. Biol. Cell. 16 (11): 5356–72. doi:10.1091/mbc.E05-07-0626. PMID 16162817.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)