Abacavir lamivudine zidovudine dosage and administration

Abacavir lamivudine zidovudine
TRIZIVIR® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

Adosage And Administration

• A Medication Guide and Warning Card that provide information about recognition of hypersensitivity reactions should be dispensed with each new prescription and refill.
• TRIZIVIR can be taken with or without food.

Adults and Adolescent Patients

The recommended oral dose of TRIZIVIR is one tablet twice daily.

TRIZIVIR is not recommended in adolescents who weigh less than 40 kg because it is a fixed-dose tablet and cannot be dose adjusted.

Dosage Adjustment

Because it is a fixed-dose combination, TRIZIVIR should not be prescribed for:

• patients requiring dosage adjustment such as those with creatinine clearance <50 mL/min.
• patients with hepatic impairment.

References

Adapted from the FDA Package Insert.