Acute mesenteric ischemia risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Rim Halaby
Overview
Acute mesenteric ischemia can be grossly divided into three main pathologies, each of which have different risk factors. Occlusive arterial mesenteric ischemia has mainly heart related problems like atrial fibrillation, CAD and heart failure as risk factors. Occlusive venous mesenteric ischemia is associated with inherited and acquired hypercoagulable state. As for non occlusive mesentenric ischemia, it is associated with digitalis use and conditions associated with systemic hypoperfusion.
Risk Factors
Occlusive Arterial Acute Mesenteric Ischemia
- Age more than 50[1]
- Atherosclerosis
- Atrial fibrillation
- Coronary artery disease
- Heart failure[2]
- Hypertension[3]
- Infection[4]
- Trauma[2]
Occlusive venous Acute Mesenteric Ischemia
Inherited Hypercoagulable State
- Factor V Laden
- Prothrombin gene mutation
- Antithrombin III deficiency
- Protein C deficiency
- Protein S deficiency[2]
Acquired Hepercoagulable State
- Malignancy
- Pancreatic cancer
- Pancreatitis
- Paraneoplasia[2]
Non Occlusive Acute Mesenteric Ischemia
- Heart surgery[1]
- Myocardial infarction
- Aortic insufficiency
- Congestive heart failure
- Dialysis[1]
- Digitalis
- Liver failure
- Kidney failure[5]
- Long term hemodialysis[2]
References
- ↑ 1.0 1.1 1.2 Brandt LJ, Boley SJ (2000). "AGA technical review on intestinal ischemia. American Gastrointestinal Association". Gastroenterology. 118 (5): 954–68. PMID 10784596.
- ↑ 2.0 2.1 2.2 2.3 2.4 Klar E, Rahmanian PB, Bücker A, Hauenstein K, Jauch KW, Luther B: Acute mesenteric ischemia: a vascular emergency. Dtsch Arztebl Int 2012; 109(14): 249–56. DOI: 10.3238/arztebl.2012.0249
- ↑ Schoots IG, Koffeman GI, Legemate DA, Levi M, van Gulik TM: Systematic review of survival after acute mesenteric ischaemia according to disease aetiology. Br J Surg 2004; 91: 17–27.
- ↑ Reinus JF, Brandt LJ, Boley SJ (1990). "Ischemic diseases of the bowel". Gastroenterol Clin North Am. 19 (2): 319–43. PMID 2194948.
- ↑ Haglund U. Mesenteric ischemia. In: Holzheimer RG, Mannick JA, editors. Surgical Treatment: Evidence-Based and Problem-Oriented. Munich: Zuckschwerdt; 2001. Available from: http://www.ncbi.nlm.nih.gov/books/NBK6883/