Adrenal atrophy epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maryam Hadipour, M.D.[2]
Overview
Generally, secondary adrenal atrophy is more common than primary adrenal atrophy and is more common in women. Clinical manifestations occur in 30s to 50s in primary and in 60s in secondary adrenal atrophy.
Incidence
It is estimated that the incidence of the disease is 4.4 to 6 new cases per million population, annually.
Prevalence
The prevalence of primary adrenal atrophy is estimated to be 93 to 144 cases per million population. In addition, secondary adrenal atrophy is more common with estimated prevalence of 150 to 280 cases per million population. Secondary adrenal atrophy is more common among women but is mainly diagnosed in their 60s.
Generally, Adrenal atrophy is more prevalent in women and may occur in any age but the clinical manifestations mainly occur in 30s to 50s.
Mortality
The mortality of the patients with adrenal atrophy is due to the lack of adrenal stress hormones impairs the body's capacity to deal adequately with stressful situations, resulting in life-threatening adrenal crises. It is estimated that one out of 200 patients with adrenal atrophy dies from adrenal crisis each year.[1][2]
References
- ↑ Feingold KR, Anawalt B, Boyce A, Chrousos G, de Herder WW, Dhatariya K, Dungan K, Hershman JM, Hofland J, Kalra S, Kaltsas G, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, Morley JE, New M, Purnell J, Sahay R, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, Nicolaides NC, Chrousos GP, Charmandari E. PMID 25905309. Missing or empty
|title=(help) - ↑ Hahner S (June 2018). "Acute adrenal crisis and mortality in adrenal insufficiency: Still a concern in 2018!". Ann Endocrinol (Paris). 79 (3): 164–166. doi:10.1016/j.ando.2018.04.015. PMID 29716733.