Adrenocortical carcinoma laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Laboratory findings

Hormonal syndromes should be confirmed with laboratory testing. The following are the lab findings in various syndromes caused by adrenocortical carcinoma.

• Cushing syndrome:
  • Increased serum glucose (blood sugar)
  • Increased urine cortisol.
• Adrenal virilism:
  • Excess serumandrostenedione
  • Excess serum dehydroepiandrosterone.
• Conn syndrome:
  • low serum potassium
  • Low plasma renin activity
  • High serum aldosterone.
• Feminization:
  • Excess serum estrogen