Anal cancer natural history

Anal cancer Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. The three major prognostic factors are site (anal canal vs. perianal skin), size (primary tumors <2 cm in size have better prognoses), and lymph nodes involvement.

Prognosis

The prognosis of anal cancer depends on the following:

• Size of tumor
• Location of anal cancer in the anus
• Spread to the lymph nodes