Anemia of chronic disease future or investigational therapies
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Investigational Therapy:
- Use of agents that alter the function of hepcidin such as hepcidin antagonists.[1]
- Agents that alter the function of hepcidin receptor (ferroportin) in order to manage the level of hepcidin.[2]
References
- ↑ Fung E, Nemeth E (November 2013). "Manipulation of the hepcidin pathway for therapeutic purposes". Haematologica. 98 (11): 1667–76. doi:10.3324/haematol.2013.084624. PMC 3815165. PMID 24186312.
- ↑ Poli M, Asperti M, Naggi A, Campostrini N, Girelli D, Corbella M, Benzi M, Besson-Fournier C, Coppin H, Maccarinelli F, Finazzi D, Arosio P (March 2014). "Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo". Blood. 123 (10): 1564–73. doi:10.1182/blood-2013-07-515221. PMC 3945865. PMID 24398330.