Anorectal pain

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2]

Causes

Common Causes

• Anal fissure
• Hemorrhoids
• Levator ani syndrome
• Proctalgia fugax

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Eczema, pruritus ani
Drug Side Effect	Cholestyramine resin, dextranomer and hyaluronic acid, hydrocortisone (topical), mesalamine, norfloxacin, orlistat, phenylephrine (topical)
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	Anal abscess, anal cancer, anal fissure, anal fistula, anal prolapse, anal thrombosis, anorectal abscess, anorectal fistula, anorectal tuberculosis, appendicitis, cauda equine tumor, chlamydia trachomatis infection, coccygodynia, colitis, colon cancer, colon polyp, constipation , Crohn's disease, cryptitis, diarrhea, diverticulitis, fecal impaction, hemorrhoids, inflammation of the sacral nerves, intergluteal pilonidal disease, intersphincteric abscess, levator ani syndrome, papillitis, perianal abscess, perianal hematoma, perianal thrombosis, presacral cyst, proctalgia fugax, proctitis, pruritus ani, radiation proctitis, rectal abscess, rectal bleeding, rectal cancer, rectal prolapse, solitary rectal ulcer syndrome, ulcerative colitis
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	Radiation proctitis
Infectious Disease	Anorectal tuberculosis, chlamydia trachomatis infection, lymphogranuloma venereum, neisseria gonorrhea infection, proctitis, prostatitis
Musculoskeletal/Orthopedic	Compression of the sacral nerves, inflammation of the sacral nerves
Neurologic	Cauda equine tumor, compression of the sacral nerves
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	Chlamydia trachomatis infection, endometriosis, ovarian cyst, pelvic inflammatory disease, uterine fibroid
Oncologic	Anal cancer, colon cancer, mucosal melanoma, perianal hematoma, prostate cancer, rectal cancer
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	No underlying causes
Trauma	Trauma
Urologic	Cauda equine tumor, compression of the sacral nerves, inflammation of the sacral nerves, prostate cancer, prostatitis
Miscellaneous	Anal sex, rectal foreign bodies

Causes in Alphabetical Order

• Anal abscess
• Anal cancer
• Anal fissure
• Anal fistula
• Anal prolapse
• Anal sex
• Anal thrombosis
• Anorectal abscess
• Anorectal fistula
• Anorectal tuberculosis
• Appendicitis
• Cauda equine tumor
• Chlamydia trachomatis infection
• Cholestyramine resin
• Coccygodynia
• Colitis
• Colon cancer
• Colon polyp
• Compression of the sacral nerves
• Constipation
• Crohn's disease
• Cryptitis
• Dextranomer and Hyaluronic acid
• Diarrhea
• Diverticulitis
• Eczema
• Endometriosis
• Fecal impaction
• Hemorrhoids
• Hydrocortisone (topical)
• Inflammation of the sacral nerves
• Intergluteal pilonidal disease
• Intersphincteric abscess
• Levator ani syndrome
• Lymphogranuloma venereum
• Mesalamine
• Mucosal melanoma
• Neisseria gonorrhea infection
• Norfloxacin
• Orlistat
• Ovarian cyst
• Papillitis
• Pelvic inflammatory disease
• Perianal abscess
• Perianal thrombosis
• Perianal hematoma
• Phenylephrine (topical)
• Presacral cyst
• Proctalgia fugax
• Proctitis
• Prostate cancer
• Prostatitis
• Pruritus ani
• Radiation proctitis
• Rectal abscess
• Rectal bleeding
• Rectal cancer
• Rectal foreign bodies
• Rectal prolapse
• Solitary rectal ulcer syndrome
• Trauma
• Ulcerative colitis
• Uterine fibroid