Antithrombin III deficiency natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
In renal failure, especially nephrotic syndrome, antithrombin is lost in the urine, leading to a higher activity of Factor II and Factor X and in increased tendency to thrombosis.
Blood clots can cause death, especially if they are in the lungs.
Prognosis
Most patients have a good outcome if they stay on anticoagulant medications.