Aortic coarctation risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S.[2], Cafer Zorkun, M.D., Ph.D. [3]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S.[4]
Overview
Risk factors associated with an increased risk of coarctation include genetic anomalies, familial history, environmental factors, and neonatal care.
Risk Factors
Like many congenital heart disease, the cause of aortic coarctation is not well defined. Clinical studies suggest that genetic and environmental factors both play an important role during pregnancy. These include:
- Genetic disorders, such as Turner syndrome. As many as 10-25% of patients with Turner syndrome have an accompanying coarctation of the aorta.
- Gender, more common in males than females (2:1 ratio).
- Viral infections during pregnancy.
- Presence of another congenital heart disease, such as: