Atherosclerosis causes
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Diagnosis |
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Atherosclerosis causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Niloofarsadaat Eshaghhosseiny, MD[2]
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Atherosclerosis Microchapters |
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Diagnosis |
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Treatment |
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ACC/AHA Guideline Recommendations |
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Case Studies |
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Atherosclerosis causes On the Web |
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American Roentgen Ray Society Images of Atherosclerosis causes |
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Risk calculators and risk factors for Atherosclerosis causes |
Overview
Atherosclerosis may be caused by inflamation,immunity or infection.Atherosclerosis is a disease with multiple genetic and environmental contributions. To review risk factors for the development of atherosclerosis, click here.
Causes
Life-threatening Causes
- Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.complications resulting from untreated atherosclerosis is common.
- Atherosclerosis is a life-threatening cause of acute cronary syndrome and stroke.
Common Causes
Common causes of atherosclerosis may include:
- Immunity
- Inflamation
- Infections,such as geram negative sepsis,can cause type 2 acute cronary syndrome.[1]
- Smoking
- HTN
- HLP
- DM
- Kidney disease
- Adiposity[2]
Less Common Causes
Less common causes of [disease name] include:
- [Cause1]
- [Cause2]
- [Cause3]
Genetic Causes
- Atherosclerosis can caused by expression in the PCSK9 gene.[3]
- Mutation one of the three genes below can cause familal hypercholesterolemia:LDLR,APOB3,PCSK9.[4]
- In human nearly 40 quantitative trait loci have been found for atherosclerosis.[5]
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
List the causes of the disease in alphabetical order:
- Cause 1
- Cause 2
- Cause 3
- Cause 4
- Cause 5
- Cause 6
- Cause 7
- Cause 8
- Cause 9
- Cause 10
References
- ↑ Libby P, Loscalzo J, Ridker PM, Farkouh ME, Hsue PY, Fuster V; et al. (2018). "Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week". J Am Coll Cardiol. 72 (17): 2071–2081. doi:10.1016/j.jacc.2018.08.1043. PMC 6196735. PMID 30336831.
- ↑ Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID doi.org/10.1161 Check
|pmid=value (help). - ↑ Ferri N, Tibolla G, Pirillo A, Cipollone F, Mezzetti A, Pacia S; et al. (2012). "Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels". Atherosclerosis. 220 (2): 381–6. doi:10.1016/j.atherosclerosis.2011.11.026. PMID 22176652.
- ↑ Sjouke B, Kusters DM, Kindt I, Besseling J, Defesche JC, Sijbrands EJ; et al. (2015). "Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome". Eur Heart J. 36 (9): 560–5. doi:10.1093/eurheartj/ehu058. PMID 24585268.
- ↑ Chen Y, Rollins J, Paigen B, Wang X (2007). "Genetic and genomic insights into the molecular basis of atherosclerosis". Cell Metab. 6 (3): 164–79. doi:10.1016/j.cmet.2007.07.001. PMC 2083632. PMID 17767904.