Atypical teratoid rhabdoid tumor other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other diagnostic studies for atypical teratoid rhabdoid tumor include biopsy (definitive diagnostic test), fluorescence in situ hybridization (abnormalities of chromosome 22q11.2), and immunohistochemistry (loss of INI-1 staining in the neoplastic cells).
Other Diagnostic Studies
Biopsy
Biopsy is performed for the definitive diagnosis of atypical teratoid rhabdoid tumor.[1]
Fluorescent In Situ Hybridization
Fluorescence in situ hybridization demonstrates abnormalities of chromosome 22q11.2.
Immunohistochemistry
Immunohistochemistry studies reveal the loss of INI-1 staining in the neoplastic cells confirming the diagnosis of atypical teratoid rhabdoid tumor.[2]
References
- ↑ Diagnostic evaluation of atypical teratoid rhabdoid tumor. National Cancer Institute 2015. http://www.cancer.gov/types/brain/hp/child-cns-atrt-treatment-pdq#link/_113_toc. Accessed on December 16, 2015
- ↑ Udaka, Y. T.; Shayan, K.; Chuang, N. A.; Crawford, J. R. (2013). "Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child". Case Reports in Oncological Medicine. 2013: 1–4. doi:10.1155/2013/815923. ISSN 2090-6706.