BMP3 (gene)
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Bone morphogenetic protein 3 (osteogenic) | |||||||||||
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Identifiers | |||||||||||
Symbols | BMP3 ; BMP-3A | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 927 | ||||||||||
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RNA expression pattern | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Bone morphogenetic protein 3 (osteogenic), also known as BMP3, is a human gene.[1]
BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation.[1]
References
Further reading
- Dickinson ME, Kobrin MS, Silan CM; et al. (1990). "Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci". Genomics. 6 (3): 505–20. PMID 1970330.
- Tabas JA, Zasloff M, Wasmuth JJ; et al. (1991). "Bone morphogenetic protein: chromosomal localization of human genes for BMP1, BMP2A, and BMP3". Genomics. 9 (2): 283–9. PMID 2004778.
- Paralkar VM, Nandedkar AK, Pointer RH; et al. (1990). "Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen". J. Biol. Chem. 265 (28): 17281–4. PMID 2211625.
- Rosen V, Wozney JM, Wang EA; et al. (1990). "Purification and molecular cloning of a novel group of BMPs and localization of BMP mRNA in developing bone". Connect. Tissue Res. 20 (1–4): 313–9. PMID 2612162.
- Wozney JM, Rosen V, Celeste AJ; et al. (1989). "Novel regulators of bone formation: molecular clones and activities". Science. 242 (4885): 1528–34. PMID 3201241.
- Faucheux C, Ulysse F, Bareille R; et al. (1998). "Opposing actions of BMP3 and TGF beta 1 in human bone marrow stromal cell growth and differentiation". Biochem. Biophys. Res. Commun. 241 (3): 787–93. doi:10.1006/bbrc.1997.7792. PMID 9434787.
- Daluiski A, Engstrand T, Bahamonde ME; et al. (2001). "Bone morphogenetic protein-3 is a negative regulator of bone density". Nat. Genet. 27 (1): 84–8. doi:10.1038/83810. PMID 11138004.
- Jin Y, Lu HB, Liong E; et al. (2002). "Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors". Histol. Histopathol. 16 (4): 1013–9. PMID 11642720.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Kloen P, Di Paola M, Borens O; et al. (2004). "BMP signaling components are expressed in human fracture callus". Bone. 33 (3): 362–71. PMID 13678778.
- Kang Q, Sun MH, Cheng H; et al. (2004). "Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery". Gene Ther. 11 (17): 1312–20. doi:10.1038/sj.gt.3302298. PMID 15269709.
- Chen AL, Fang C, Liu C; et al. (2004). "Expression of bone morphogenetic proteins, receptors, and tissue inhibitors in human fetal, adult, and osteoarthritic articular cartilage". J. Orthop. Res. 22 (6): 1188–92. doi:10.1016/j.orthres.2004.02.013. PMID 15475196.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
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