BTG4

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	Wikidata
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Protein BTG4 also known as BTG family member 4 is a protein that in humans is encoded by the BTG4 gene (B-cell translocation gene 4).^[1]^[2] BTG4 has anti-proliferative properties and can induce G₁ cell cycle arrest.^[2]

References

↑ "Entrez Gene: B-cell translocation gene 4".
↑ ^2.0 ^2.1 Buanne P, Corrente G, Micheli L, Palena A, Lavia P, Spadafora C, Lakshmana MK, Rinaldi A, Banfi S, Quarto M, Bulfone A, Tirone F (September 2000). "Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium". Genomics. 68 (3): 253–63. doi:10.1006/geno.2000.6288. PMID 10995567.

External links

Human BTG4 genome location and BTG4 gene details page in the UCSC Genome Browser.

Auer RL, Starczynski J, McElwaine S, et al. (2005). "Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia". Genes Chromosomes Cancer. 43 (1): 1–10. doi:10.1002/gcc.20159. PMID 15672409.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Dong W, Tu S, Xie J, et al. (2009). "Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer". Biochem. Biophys. Res. Commun. 387 (1): 132–8. doi:10.1016/j.bbrc.2009.06.140. PMID 19576178.
Yoshida Y, Hosoda E, Nakamura T, Yamamoto T (2001). "Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex". Jpn. J. Cancer Res. 92 (6): 592–6. doi:10.1111/j.1349-7006.2001.tb01135.x. PMID 11429045.
Toyota M, Suzuki H, Sasaki Y, et al. (2008). "Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer". Cancer Res. 68 (11): 4123–32. doi:10.1158/0008-5472.CAN-08-0325. PMID 18519671.
Tirone F (2001). "The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?". J. Cell. Physiol. 187 (2): 155–65. doi:10.1002/jcp.1062. PMID 11267995.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: B-cell translocation gene 4".

[pmid10995567-2] 2.0 ^2.1 Buanne P, Corrente G, Micheli L, Palena A, Lavia P, Spadafora C, Lakshmana MK, Rinaldi A, Banfi S, Quarto M, Bulfone A, Tirone F (September 2000). "Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium". Genomics. 68 (3): 253–63. doi:10.1006/geno.2000.6288. PMID 10995567.

[1]

[2]

BTG4

References

External links

Further reading

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