BTN1A1

Butyrophilin, subfamily 1, member A1
Identifiers
Symbols	BTN1A1 ; BT; BTN
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1312
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Butyrophilin, subfamily 1, member A1, also known as BTN1A1, is a human gene.

Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families

Further reading

• Mather IH, Jack LJ (1994). "A review of the molecular and cellular biology of butyrophilin, the major protein of bovine milk fat globule membrane". J. Dairy Sci. 76 (12): 3832–50. PMID 8132890.
• Heid HW, Winter S, Bruder G; et al. (1983). "Butyrophilin, an apical plasma membrane-associated glycoprotein characteristic of lactating mammary glands of diverse species". Biochim. Biophys. Acta. 728 (2): 228–38. PMID 6830779.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sato T, Takio K, Kobata A; et al. (1995). "Site-specific glycosylation of bovine butyrophilin". J. Biochem. 117 (1): 147–57. PMID 7775382.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vernet C, Boretto J, Mattéi MG; et al. (1994). "Evolutionary study of multigenic families mapping close to the human MHC class I region". J. Mol. Evol. 37 (6): 600–12. PMID 8114113.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Taylor MR, Peterson JA, Ceriani RL, Couto JR (1996). "Cloning and sequence analysis of human butyrophilin reveals a potential receptor function". Biochim. Biophys. Acta. 1306 (1): 1–4. PMID 8611614.CS1 maint: Multiple names: authors list (link)
• Tazi-Ahnini R, Henry J, Offer C; et al. (1998). "Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex". Immunogenetics. 47 (1): 55–63. PMID 9382921.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cavaletto M, Giuffrida MG, Giunta C; et al. (1999). "Multiple forms of lactadherin (breast antigen BA46) and butyrophilin are secreted into human milk as major components of milk fat globule membrane". J. Dairy Res. 66 (2): 295–301. PMID 10376248.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shibui A, Tsunoda T, Seki N; et al. (1999). "Cloning, expression analysis, and chromosomal localization of a novel butyrophilin-like receptor". J. Hum. Genet. 44 (4): 249–52. PMID 10429365.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rhodes DA, Stammers M, Malcherek G; et al. (2001). "The cluster of BTN genes in the extended major histocompatibility complex". Genomics. 71 (3): 351–62. doi:10.1006/geno.2000.6406. PMID 11170752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• McManaman JL, Palmer CA, Wright RM, Neville MC (2003). "Functional regulation of xanthine oxidoreductase expression and localization in the mouse mammary gland: evidence of a role in lipid secretion". J. Physiol. (Lond.). 545 (Pt 2): 567–79. PMID 12456835.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Woo JS, Imm JH, Min CK; et al. (2006). "Structural and functional insights into the B30.2/SPRY domain". EMBO J. 25 (6): 1353–63. doi:10.1038/sj.emboj.7600994. PMID 16498413.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)