Basophilic leukocytes

Basophilic leukocytes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

• Basophilic leukocytes are named for the ability of their cytoplasmic granules to stain with basic dyes
• Basophilic leukocytes contain and can release histamine and serotonin
• Reference range: 0.5-3.0% (least common leukocyte)

Differential Diagnosis

Increased

• Allergic diathesis
• Asthma
• Chickenpox
• Chronic inflammatory processes
• Chronic Myelogenous Leukemia (CML)
• Chronic sinusitis
• Diabetes Mellitus
• Estrogen therapy
• Following splenectomy
• Hodgkin's Lymphoma
• Hyperthyroidism
• Hypothyroidism
• Idiopathic thrombocythemia
• Influenza
• Mastocytosis
• Osteomyelosclerosis
• Polycythemia Vera
• Radiation exposure
• Tuberculosis
• Ulcerative colitis

Decreased

• Corticosteroids
• Hypersensitivity reaction
• Hyperthyroidism
• Pregnancy
• Stress

References

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