Bradford Hill criteria

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In evidence-based medicine, Bradford Hill criteria were proposed in 1965 and help assess the likelihood of causation.

The criteria

The criteria are:

• Strength or magnitude of association?
• Consistency of association across studies?
• Specificity of association?
• Temporality of association?
• Plausibility based on biological knowledge?
• Biological gradient: or dose-response relationship?
• Coherence? Does the proposed association explain other observations?
• Experimental evidence?
• Analogy?

See also

• Koch's postulates