Brilinta tablet/contraindications

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Brilinta tablet®
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Adult Indications and Dosage
Pediatric Indications and Dosage
Contraindications
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Adverse Reactions
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]

Contraindications

History of Intracranial Hemorrhage

BRILINTA is contraindicated in patients with a history of intracranial hemorrhage (ICH) because of a high risk of recurrent ICH in this population (see Clinical Studies).

Active Bleeding

BRILINTA is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage (see Warnings and Adverse Reactions).

Severe Hepatic Impairment

BRILINTA is contraindicated in patients with severe hepatic impairment because of a probable increase in exposure, and it has not been studied in these patients. Severe hepatic impairment increases the risk of bleeding because of reduced synthesis of coagulation proteins (see Pharmacology).

Hypersensivity

BRILINTA is contraindicated in patients with hypersensitivity (e.g. angioedema) to ticagrelor or any component of the product (see Adverse Reactions)[1].

References

  1. "BRILINTA (TICAGRELOR) TABLET [ASTRAZENECA LP]". Retrieved 21 March 2014.