Buerger's disease diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Although clinical examination is sufficient for diagnosis, in cases where diagnosis is not definitive, a catheter-based arteriogram is the gold standard test for the diagnosis of Buerger disease. The following result of catheter-based arteriogram is confirmatory of Buerger disease and includes, absence of atherosclerosis, no cause for thromboembolism, small and medium-sized vessels involved, namely tibial, popliteal, and radial arteries, segmental affection of vessels between normal appearing segments and corkscrew collaterals described as collateralizations around an occlusion area but are not pathognomonic.

Diagnostic Study of Choice

Study of choice

  • Although clinical examination is sufficient for diagnosis, in cases where diagnosis is not definitive, a catheter-based arteriogram is the gold standard test for the diagnosis of Buerger disease.[1][2][1][3]
  • The following result of catheter-based arteriogram is confirmatory of Buerger disease:
    • Absence of atherosclerosis
    • No cause for thromboembolism
    • Small and medium-sized vessels involved, namely tibial, popliteal, and radial arteries
    • Segmental affection of vessels between normal appearing segments
    • Corkscrew collaterals described as collateralization around occlusion area but are not pathognomonic
Sequence of Diagnostic Studies
  • The catheter-based arteriogram should be performed when:[4]
    • The patient presents with symptoms and signs that are consistent with Buerger's disease but not definite.

Diagnostic Criteria

  • The diagnosis of Buerger's disease is based on the Shionoya's criteria, which includes:[5][6][7]
    • Less than 45 years old
    • Past or current history of tobacco intake
    • Ischemia of the distal extremities
    • Arteriographic findings suggestive of thromboangiitis obliterans
    • Exclusion of another organic cause such as a source of embolism, autoimmune disease, thrombophilia, or diabetes mellitus.

References

  1. 1.0 1.1 Lambeth JT, Yong NK (July 1970). "Arteriographic findings in thromboangiitis obliterans with emphasis on femoropopliteal involvement". Am J Roentgenol Radium Ther Nucl Med. 109 (3): 553–62. PMID 5431503.
  2. Dimmick SJ, Goh AC, Cauzza E, Steinbach LS, Baumgartner I, Stauffer E, Voegelin E, Anderson SE (December 2012). "Imaging appearances of Buerger's disease complications in the upper and lower limbs". Clin Radiol. 67 (12): 1207–11. doi:10.1016/j.crad.2012.04.005. PMID 22784658.
  3. Yoshimuta T, Akutsu K, Okajima T, Tamori Y, Kubota Y, Takeshita S (June 2009). "Corkscrew collaterals in Buerger's disease". Can J Cardiol. 25 (6): 365. PMC 2722480. PMID 19536378.
  4. Piazza G, Creager MA (April 2010). "Thromboangiitis obliterans". Circulation. 121 (16): 1858–61. doi:10.1161/CIRCULATIONAHA.110.942383. PMC 2880529. PMID 20421527.
  5. Shionoya S (October 1998). "Diagnostic criteria of Buerger's disease". Int. J. Cardiol. 66 Suppl 1: S243–5, discussion S247. PMID 9951826.
  6. Shionoya S (July 1983). "What is Buerger's disease?". World J Surg. 7 (4): 544–51. PMID 6624130.
  7. Lazarides MK, Georgiadis GS, Papas TT, Nikolopoulos ES (June 2006). "Diagnostic criteria and treatment of Buerger's disease: a review". Int J Low Extrem Wounds. 5 (2): 89–95. doi:10.1177/1534734606288817. PMID 16698911.

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