Chromosome 6 open reading frame 201 (C6orf201) is also referred to as: dJ1013A10.5, MGC87625, RP5-1013A10.5, and LOC404220.[6]
Locus
C6orf201 is located on chromosome 6 at 6p25.2 position and is encoded on the plus strand.[7]C6orf201 is located near the FAM217A gene and the ECI2 gene.[8]
File:Human GEO profile.PNGExpression of C6orf201 in various human tissues showing highest expression in the testis.File:Mouse GEO profile.PNGExpression of C6orf201 in various mouse tissues showing highest expression in the testis.
Clinical relevance
Research Results
A toxicology study revealed that C6orf201 was one of the top 20 deregulated genes in monkeys that had been exposed to welding fumes for an extended period of time.[19] Another study investigated gene expression after the use of a methylation inhibitor, C6orf201 being one of many genes investigated.[20]
References
↑Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, et al. (October 2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID14574404.
↑ 2.02.1"EST Profile". National Center for Biotechnology Information. Retrieved 9 May 2015.
↑Varjosalo M, Keskitalo S, Van Drogen A, Nurkkala H, Vichalkovski A, Aebersold R, Gstaiger M (April 2013). "The protein interaction landscape of the human CMGC kinase group". Cell Reports. 3 (4): 1306–20. doi:10.1016/j.celrep.2013.03.027. PMID23602568.
↑Park GT, Han J, Park SG, Kim S, Kim TY (April 2014). "DNA methylation analysis of CD4+ T cells in patients with psoriasis". Archives of Dermatological Research. 306 (3): 259–68. doi:10.1007/s00403-013-1432-8. PMID24323136.