CENTA1

Centaurin, alpha 1
Identifiers
Symbols	CENTA1 ; GCS1L; p42IP4
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55997
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Centaurin, alpha 1, also known as CENTA1, is a human gene.

Further reading

• Venkateswarlu K, Oatey PB, Tavaré JM; et al. (1999). "Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1". Biochem. J. 340 ( Pt 2): 359–63. PMID 10333475.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Venkateswarlu K, Cullen PJ (1999). "Molecular cloning and functional characterization of a human homologue of centaurin-alpha". Biochem. Biophys. Res. Commun. 262 (1): 237–44. doi:10.1006/bbrc.1999.1065. PMID 10448098.
• Dubois T, Kerai P, Zemlickova E; et al. (2001). "Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins". J. Biol. Chem. 276 (22): 18757–64. doi:10.1074/jbc.M010005200. PMID 11278595.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sedehizade F, Hanck T, Stricker R; et al. (2002). "Cellular expression and subcellular localization of the human Ins(1,3,4,5)P(4)-binding protein, p42(IP4), in human brain and in neuronal cells". Brain Res. Mol. Brain Res. 99 (1): 1–11. PMID 11869802.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Whitley P, Gibbard AM, Koumanov F; et al. (2003). "Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle". Eur. J. Cell Biol. 81 (4): 222–30. PMID 12018390.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Reiser G, Bernstein HG (2003). "Neurons and plaques of Alzheimer's disease patients highly express the neuronal membrane docking protein p42IP4/centaurin alpha". Neuroreport. 13 (18): 2417–9. doi:10.1097/01.wnr.0000048005.96487.10. PMID 12499840.
• Dubois T, Zemlickova E, Howell S, Aitken A (2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochem. Biophys. Res. Commun. 301 (2): 502–8. PMID 12565890.CS1 maint: Multiple names: authors list (link)
• Matsuda A, Suzuki Y, Honda G; et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zemlickova E, Dubois T, Kerai P; et al. (2003). "Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.". Biochem. Biophys. Res. Commun. 307 (3): 459–65. PMID 12893243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Venkateswarlu K, Brandom KG, Lawrence JL (2004). "Centaurin-alpha1 is an in vivo phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein for ARF6 that is involved in actin cytoskeleton organization". J. Biol. Chem. 279 (8): 6205–8. doi:10.1074/jbc.C300482200. PMID 14625293.CS1 maint: Multiple names: authors list (link)
• Hanck T, Stricker R, Sedehizade F, Reiser G (2004). "Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins". J. Neurochem. 88 (2): 326–36. PMID 14690521.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Reiser G, Bernstein HG (2004). "Altered expression of protein p42IP4/centaurin-alpha 1 in Alzheimer's disease brains and possible interaction of p42IP4 with nucleolin". Neuroreport. 15 (1): 147–8. PMID 15106847.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Thacker E, Kearns B, Chapman C; et al. (2005). "The arf6 GAP centaurin alpha-1 is a neuronal actin-binding protein which also functions via GAP-independent activity to regulate the actin cytoskeleton". Eur. J. Cell Biol. 83 (10): 541–54. PMID 15679100.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lawrence J, Mundell SJ, Yun H; et al. (2005). "Centaurin-alpha 1, an ADP-ribosylation factor 6 GTPase activating protein, inhibits beta 2-adrenoceptor internalization". Mol. Pharmacol. 67 (6): 1822–8. doi:10.1124/mol.105.011338. PMID 15778454.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hayashi H, Matsuzaki O, Muramatsu S; et al. (2006). "Centaurin-alpha1 is a phosphatidylinositol 3-kinase-dependent activator of ERK1/2 mitogen-activated protein kinases". J. Biol. Chem. 281 (3): 1332–7. doi:10.1074/jbc.M505905200. PMID 16287813.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sedehizade F, von Klot C, Hanck T, Reiser G (2006). "p42(IP4)/centaurin alpha1, a brain-specific PtdIns(3,4,5)P3/Ins(1,3,4,5)P4-binding protein: membrane trafficking induced by epidermal growth factor is inhibited by stimulation of phospholipase C-coupled thrombin receptor". Neurochem. Res. 30 (10): 1319–30. doi:10.1007/s11064-005-8804-1. PMID 16341594.CS1 maint: Multiple names: authors list (link)