CMV pneumonitis natural history
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Natural history
Complications
Complications of CMV infection in people with AIDS include:
- CMV pneumonia.
- Esophageal disease.
- Intestinal disease.
- Infectious, mononucleosis-like illness (CMV mononucleosis).
- Inflammation of the retina (CMV retinitis).
Complications of CMV pneumonia include:
- Kidney impairment (from drugs used to treat the condition).
- Low white blood cell count (from drugs used to treat the condition).
- Overwhelming infection that doesn't respond to treatment.
- Return of infections.
Prognosis
Prognosis is poor. Particularly in significantly immunocompromised hosts, mortality from significant CMV pneumonitis may be greater than 50%.