Carbenicillin indanyl sodium adverse reactions

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Carbenicillin indanyl sodium
GEOCILLIN® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Adverse Reactions

The following adverse reactions have been reported as possibly related to Geocillin administration in controlled studies which include 344 patients receiving Geocillin.

Gastrointestinal

The most frequent adverse reactions associated with Geocillin therapy are related to the gastrointestinal tract. Nausea, bad taste, diarrhea, vomiting, flatulence, and glossitis were reported. Abdominal cramps, dry mouth, furry tongue, rectal bleeding, anorexia, and unspecified epigastric distress were rarely reported.

Dermatologic

Hypersensitivity reactions such as skin rash, urticaria, and less frequently pruritus.

Hematologic

As with other penicillins, anemia, thrombocytopenia, leukopenia, neutropenia, and eosinophilia have infrequently been observed. The clinical significance of these abnormalities is not known.

Miscellaneous

Other reactions rarely reported were hyperthermia, headache, itchy eyes, vaginitis, and loose stools.

Abnormalities of Hepatic Function Tests

Mild SGOT elevations have been observed following Geocillin administration.[1]

References

  1. "GEOCILLIN (CARBENICILLIN INDANYL SODIUM) TABLET, FILM COATED [ROERIG]". Text " accessdate" ignored (help)

Adapted from the FDA Package Insert.