Cavernous sinus thrombosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

The prevalence of cavernous sinus thrombosis is approximately 1.32–1.57 per 100,000 individuals worldwide. The mortality rate of cavernous sinus thrombosis is approximately 20%. The combination of anticoagulants with antibiotics in treatment of cavernous sinus thrombosis has significantly decreased the mortality rate of it. Patients of all age groups may develop cavernous sinus thrombosis. The incidence of cavernous sinus thrombosis significantly increases with age. women are more commonly affected by cavernous sinus thrombosis than men. The women to men ratio is approximately 3.7–5.3 to 1.

Epidemiology and Demographics

Incidence

  • The prevalence of cavernous sinus thrombosis is approximately 1.32–1.57 per 100,000 individuals worldwide.[1][2]

Case-fatality rate/Mortality rate

  • The mortality rate of cavernous sinus thrombosis is approximately 20%.[3]

The combination of anticoagulants with antibiotics in treatment of cavernous sinus thrombosis has significantly decreased the mortality rate of it.[4]

Age

  • Patients of all age groups may develop cavernous sinus thrombosis.
  • The incidence of cavernous sinus thrombosis significantly increases with age.[4][5]

Gender

  • Women are more commonly affected by cavernous sinus thrombosis than men. The women to men ratio is approximately 3.7–5.3 to 1.[2][5]

References

  1. Devasagayam S, Wyatt B, Leyden J, Kleinig T (2016). "Cerebral Venous Sinus Thrombosis Incidence Is Higher Than Previously Thought: A Retrospective Population-Based Study". Stroke. 47 (9): 2180–2. doi:10.1161/STROKEAHA.116.013617. PMID 27435401.
  2. 2.0 2.1 Luo Y, Tian X, Wang X (2018). "Diagnosis and Treatment of Cerebral Venous Thrombosis: A Review". Front Aging Neurosci. 10: 2. doi:10.3389/fnagi.2018.00002. PMC 5797620. PMID 29441008.
  3. Arian M, Kamali A, Tabatabaeichehr M, Arashnia P (2016). "Septic Cavernous Sinus Thrombosis: A Case Report". Iran Red Crescent Med J. 18 (8): e34961. doi:10.5812/ircmj.34961. PMC 5068248. PMID 27781123.
  4. 4.0 4.1 Leo QJ, Bolger DT (2014). "Septic cavernous sinus thrombosis due to Campylobacter rectus infection". BMJ Case Rep. 2014. doi:10.1136/bcr-2013-203351. PMC 4039913. PMID 24842357.
  5. 5.0 5.1 Karadas S, Milanlioglu A, Gönüllü H, Sayin R, Aydin MN (2014). "Cerebral venous sinus thrombosis presentation in emergency department in Van, Turkey". J Pak Med Assoc. 64 (4): 370–4. PMID 24864625.

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