Cefpirome adverse reactions
Cefpirome |
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CEFROM® Package Insert |
Composition |
Properties |
Indications |
Microbiology |
Contraindications |
Warnings and Precautions |
Adverse Reactions |
Drug Interactions |
Dosage and Administration |
How Supplied |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Adverse Reactions
Hypersensitivity reactions: Allergic skin reactions (rash, urticaria), itching, drug fever and severe acute allergic (anaphylactic) reactions may occur.
Effects on the gastrointestinal tract: Nausea and vomiting, abdominal pain, diarrhea in very rare cases of pseudomembranous colitis.
Effects on liver function: Raise in serum liver enzymes (AST, ALT, LDH, alkaline phosphatase), increase in serum bilirubin.
Effects on renal function: Increases in serum creatinine (in rare cases necessitating discontinuation of treatment) and urea. In rare instances, interstitial nephritis may occur with cephalosporins.
Changes in blood constituents: Thrombocytopenia; eosinophilia; very rarely hemotytic anaemia. As with other beta laclam antibiotics (particularly if given over long periods), granulocytopenia and, more rarefy, agranulocytosis may develop.
Local reactions: Inflammatory irritation and pain at the injection site.
Other reactions: Disturbance of taste may be experienced immediately after injection. Headache may develop. In very few cases, convulsion.
Administration of antibiotics including Cefrom-especially if prolonged, may lead to the proliferation of resistant micro-organisms. The patient's condition must therefore be checked at regular intervals. Should a secondary infection occur, appropriate measures must be taken.[1]
References
- ↑ "http://pk.sanofi-aventis.com/products/Cefrom.pdf" (PDF). External link in
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