Central pontine myelinolysis diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Brain MRI is the gold standard test for the diagnosis of central pontine myelinolysis. The following findings on performing Brain MRI are confirmatory for central pontine myelinolysis: T2 hyperintensity in the central pontine region in the axial plane and hyperintense lesion in the midpons in the midsagittal T2-weighted MRI.

Diagnostic Study of Choice

Study of choice

Brain MRI is the gold standard test for the diagnosis of central pontine myelinolysis.^[1]

Diagnostic results

The following findings on performing Brain MRI are confirmatory for central pontine myelinolysis:^[1]^[2]

T2 hyperintensity in the central pontine region in the axial plane
Hyperintense lesion in the midpons in the midsagittal T2-weighted MRI

References

↑ ^1.0 ^1.1 Lambeck J, Hieber M, Dreßing A, Niesen WD (2019). "Central Pontine Myelinosis and Osmotic Demyelination Syndrome". Dtsch Arztebl Int. 116 (35–36): 600–606. doi:10.3238/arztebl.2019.0600. PMC 6804268 Check |pmc= value (help). PMID 31587708.
↑ Thompson PD, Miller D, Gledhill RF, Rossor MN (1989). "Magnetic resonance imaging in central pontine myelinolysis". J Neurol Neurosurg Psychiatry. 52 (5): 675–7. doi:10.1136/jnnp.52.5.675. PMC 1032189. PMID 2732743.

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[pmid31587708-1] 1.0 ^1.1 Lambeck J, Hieber M, Dreßing A, Niesen WD (2019). "Central Pontine Myelinosis and Osmotic Demyelination Syndrome". Dtsch Arztebl Int. 116 (35–36): 600–606. doi:10.3238/arztebl.2019.0600. PMC 6804268 Check |pmc= value (help). PMID 31587708.

[pmid2732743-2] Thompson PD, Miller D, Gledhill RF, Rossor MN (1989). "Magnetic resonance imaging in central pontine myelinolysis". J Neurol Neurosurg Psychiatry. 52 (5): 675–7. doi:10.1136/jnnp.52.5.675. PMC 1032189. PMID 2732743.

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