Chancroid differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Nate Michalak, B.A.; Serge Korjian M.D.
Overview
Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy including syphilis, herpes simplex, Behçet's disease, lymphogranuloma venereum, donovanosis, and fixed drug eruption.
Differentiating Chancroid from Other Diseases
Chancroid must be differentiated from other diseases that cause genital ulcers and lymphadenopathy:
- Syphilis
- Herpes simplex
- Behçet's disease
- Lymphogranuloma venereum
- Donovanosis
- Fixed drug eruption
- Psoriasis
Syphilitic chancres most closely resemble chancroid lesions. A comparison is found below:[1]
| Clinical Characteristic | Disease | |
|---|---|---|
| Syphilitic Chancre | Chancroid | |
| Mode of Transmission | Mainly sexual | Mainly sexual |
| Cause | Treponema pallidum | Haemophilus ducreyi |
| Lesion Type | Pustules that may progress to ulcers | Pustules that may progress to ulcers |
| Lesion Pain | Typically absent | Typically present |
| Lesion Location | Typically genitals | Typically genitals; may occur on limbs |
| Lesion Size | Typically 1-2 cm in diameter | Typically 1-2 cm in diameter |
| Lesion Number | Multiple | 1-4 |
| Lesion Exudate | Typically non-exudative | Typically grey/yellow purulent exudate |
| Lesion Texture | Typically indurated | Typically soft |
| Lymphadenopathy | Typically present | Occurs in approx. half of patients |
References
- ↑ Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2016.