Chlorobutanol
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Template:Chembox new Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Chlorobutanol, or 1,1,1-trichloro-2-methyl-2-propanol, is a chemical preservative, sedative hypnotic and weak local anaesthetic similar in nature to chloral hydrate.
Chemical synthesis
Chlorobutanol is formed by the simple nucleophilic addition of chloroform and acetone. The reaction is base driven by potassium or sodium hydroxide.