Cidofovir overdosage
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overdosage
Two cases of cidofovir overdose have been reported. These patients received single doses of VISTIDE at 16.3 mg/kg and 17.4 mg/kg, respectively, with concomitant oral probenecid and intravenous hydration. In both cases, the patients were hospitalized and received oral probenecid (one gram three times daily) and vigorous intravenous hydration with normal saline for 3 to 5 days. Significant changes in renal function were not observed in either patient.[1]
References
- ↑ "http://www.accessdata.fda.gov/drugsatfda_docs/label/1999/020638s003lbl.pdf" (PDF). External link in
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Adapted from the FDA Package Insert.