Chloride potassium symporter
(Redirected from Cl-K cotransporter)
The chloride potassium symporter is a membrane transport protein that is present in the S3-segment of the renal proximal tubule[1]. It functions in renal chloride reabsorption to transport chloride across the basolateral membrane.[1]
They can lower intracellular chloride concentrations below the electrochemical equilibrium potential.[2]
They are of solute carrier family 12.
Types
Types of chloride potassium symporter are:
Each is encoded by a separate gene.
The preceding symporters are actually other types of ion pumps. Member 3, for instance, is the sodium-chloride symporter.
References
- ↑ 1.0 1.1 Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 780
- ↑ "Entrez Gene: SLC12A5 solute carrier family 12, (potassium-chloride transporter) member 5".
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