Clindamycin hydrochloride overdosage
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Clindamycin hydrochloride |
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CLEOCIN HYDROCHLORIDE® FDA Package Insert |
Description |
Clinical Pharmacology |
Microbiology |
Indications and Usage |
Contraindications |
Warnings |
Precautions |
Adverse Reactions |
Overdosage |
Dosage and Administration |
How Supplied |
Labels and Packages |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
OVERDOSAGE
Significant mortality was observed in mice at an intravenous dose of 855 mg/kg and in rats at an oral or subcutaneous dose of approximately 2618 mg/kg. In the mice, convulsions and depression were observed.
Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum.
References
http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/50162s082,50441s045,50639s013lbl.pdf