Complement mediated glomerular disorders
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]
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Click here for information about C3 glomerulopathy
Click here for information about C4 glomerulopathy
Overview
Brief overview describing the two entities, their similarities and differences here.
Synopsis
Glomerular disorder | Diagnosis | Management | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Laboratory Findings | Physical Examination | ||||||||||||
C3 | C4 | Proteinuria | Hematuria | Edema | Physical Finding 2 | Physical Finding 3 | Physical Finding 4 | Corticosteroids | IV Fluids | Tx 3 | Tx 4 | Tx 5 | |
C3 glomerulopathy | ↓ | ↑ | ++ | ✘ | ✔ | ||||||||
C4 glomerulopathy | ↑ | ↑ | ✘ | ✔ |
Differential Diagnosis
Glomerular disorder | Laboratory Findings | Physical Examination | Other Findings | ||||||
---|---|---|---|---|---|---|---|---|---|
C3 | C4 | Proteinuria | Hematuria | Edema | Physical Finding 2 | Physical Finding 3 | Physical Finding 4 | ||
C3 glomerulopathy | ↓ | ↑ | ++ | ✘ | |||||
C4 glomerulopathy | ↑ | ↑ | ✘ | ||||||
Differential Diagnosis 3 | |||||||||
Differential Diagnosis 4 | |||||||||
Differential Diagnosis 5 |