Corticovirus
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| Corticovirus | ||||
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| Virus classification | ||||
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The Corticovirus or Corticoviridae are a family of phages that consist of a round, icosahedral, non-enveloped capsid of a diameter of 60 nm and an internal lipid membrane located between outer and inner protein shell[1]. The shells are composed of three layers which surfaces reveals a pattern with distinctive features[2], including bush-like spikes protruding from the twelve vertices[3].
Genome
The genome is not segmented, constitutes 13% of the virus's weight and contains a single molecule of circular, supercoiled, double-stranded DNA of 9500-12000 nucleotides in length. The genome has a g + c content of 43%[4].
Literature
- ↑ Kiveld, H.M., Kalkkinen, N. and Bamford, D.H. (2002). Bacteriophage PM2 has a protein capsid surrounding a spherical lipid-protein core. J. Virol., 76, 8169-8178.
- ↑ Kiveld, H.M., Männistö, R.H., Kalkkinen, N. and Bamford, D.H. (1999). Purification and protein composition of PM2, the first lipid-containing bacterial virus to be isolated. Virology, 262, 364-374.
- ↑ Harrison, S.C., Caspar, D.L., Camerini-Otero, R.D. and Franklin, R.M. (1971). Lipid and protein arrangement in bacteriophage PM2. Nat. New Biol., 229, 197-201.
- ↑ Männistö, R.H., Kivelä, H.M., Paulin, L., Bamford, D.H. and Bamford, J.K.H. (1999). The complete genome sequence of PM2, the first lipid-containing bacterial virus to be isolated. Virology, 262, 355-363.