Creutzfeldt-Jakob disease electrocardiogram

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

EEG findings are not diagnostic of CJD, but may help in the diagnosis of CJD. Periodic synchronous discharges (PSDs) occur either before or in synchronicity with myoclonus. Typical EEG findings in Creutzfeldt-Jakob disease include periodic biphasic or triphasic sharp wave complexes (PSWCs). Periodic sharp wave complexes can differentiate sporadic Creutzfeldt-Jakob disease‬ (present waves) from familial and variant types of Creutzfeldt-Jakob disease‬ and other prion diseases (absent waves).

Electroencephalography

• EEG findings are not diagnostic of CJD, but may help in the diagnosis of CJD.
• Periodic synchronous discharges (PSDs) occur either before or in synchronicity with myoclonus.
• Typical EEG findings in Creutzfeldt-Jakob disease include periodic biphasic or triphasic sharp wave complexes (PSWCs).
• Periodic sharp wave complexes can differentiate sporadic Creutzfeldt-Jakob disease‬ (present waves) from familial and variant types of Creutzfeldt-Jakob disease‬ and other prion diseases (absent waves).