Cutaneous abscess secondary prevention

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Abscess Main page

Patient Information

Overview

Causes

Classification

Anal Abscess
Appendicular Abscess
Brain Abscess
Breast Abscess
Colon Abscess
Cutaneous Abscess
Liver Abscess
Lung Abscess
Pancreatic Abscess
Retropharyngeal Abscess
Splenic Abscess
Tonsillar and Peritonsillar Abscess

Differential Diagnosis

To prevent recurrent infections due to Staphylococcus aureus, consider the following measures:

  • Topical mupirocin applied to the nares.[1] In this randomized controlled trial, patients used nasal mupirocin twice daily 5 days a month for 1 year.[2] The does is about 1 centimeter of ointment on a swab applied to each nares.[3]
  • Chlorhexidine baths,[4] in a randomized controlled trial, nasal recolonization with S. aureus occurred at 12 weeks in 24% of nursing home residents receiving mupirocin ointment alone (6/25) and in 15% of residents receiving mupirocin ointment plus chlorhexidine baths daily for the first three days of mupirocin treatment (4/27). Although these results did not reach statistical significance, the baths are easy to do.

References

  1. van Rijen M, Bonten M, Wenzel R, Kluytmans J (2008). "Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers". Cochrane Database Syst Rev (4): CD006216. doi:10.1002/14651858.CD006216.pub2. PMID 18843708.
  2. Raz R, Miron D, Colodner R, Staler Z, Samara Z, Keness Y (1996). "A 1-year trial of nasal mupirocin in the prevention of recurrent staphylococcal nasal colonization and skin infection". Arch Intern Med. 156 (10): 1109–12. PMID 8638999.
  3. Harbarth S, Dharan S, Liassine N, Herrault P, Auckenthaler R, Pittet D (1999). "Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus". Antimicrob. Agents Chemother. 43 (6): 1412–6. PMC 89288. PMID 10348762. Unknown parameter |month= ignored (help)
  4. Watanakunakorn C, Axelson C, Bota B, Stahl C (1995). "Mupirocin ointment with and without chlorhexidine baths in the eradication of Staphylococcus aureus nasal carriage in nursing home residents". Am J Infect Control. 23 (5): 306–9. PMID 8585642.

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