Cytome

Overview

Cytomes are the cellular systems, subsystems, and functional components of the body. The cytome is the collection of the complex and dynamic cellular processes (structure and function) underlying physiological processes. It describes the structural and functional heterogeneity of the cellular diversity of an organism. The study of cytomes is called Cytomics.

The Human Cytome Project is about the study of the biological system structure and function of an organism at the cytome level. It relates to Cytomics, which is the study of cell systems (cytomes) at a single cell level. At the Focus on Microscopy (FOM) meeting in Philadelphia, on Wednesday afternoon, 7 April 2004, the idea of a Human Cytome Project was for the first time discussed at a scientific meeting.

See also

• Cytomics
• Cell biology
• Human Genome Project
• EuroPhysiome
• Lipidomics

References

• Davies E, Stankovic B, Azama K, Shibata K, Abe S., Novel components of the plant cytoskeleton: A beginning to plant "cytomics", Plant Science, Invited Review, Plant Science 2001; (160)2: 185-196.
• Fenech M., Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death., Mutat Res. 2006 Aug 30;600(1-2):58-66.
• Galle J, Aust G, Schaller G, Beyer T, Drasdo D., Individual cell-based models of the spatial-temporal organization of multicellular systems--achievements and limitations, Cytometry A. 2006 Jul;69(7):704-10.
• Valet G, Tarnok A, Potential and challenges of a human cytome project, J Biol Regul Homeost Agents, 2004, Apr-Jun;18(2): 87-91.
• Valet G., Cytomics: an entry to biomedical cell systems biology, Cytometry A. 2005 Feb; 63(2):67-8.
• Perez OD, Nolan GP., Phospho-proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single-cell level, Immunol Rev. 2006 Apr;210:208-28.