Defibrination syndrome

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Fibrinolysis syndrome (also known as "Defibrinating syndrome") is characterized by an acute hemorrhagic state brought about by inability of the blood to clot, with massive hemorrhages into the skin producing blackish, purplish swellings and sloughing.[1]:826

Cause

The cause for Fibrinolysis syndrome, is the inability of the body to produce blood-coagulates to stop bleeding. What causes the body to not produce blood-coagulates are the low levels of fibrin, or therefore non-existent fibrin.[2]

Symptoms

Hemorrhages (this includes severe bleeding of any particular area. Be it: nasal, rectal, oral, it also includes bleeding from scrapes, cuts, bruises (big bruises that do not disappear in the first two to three days).

See also

References

  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. Merskey, C.; Johnson, A. J.; Kleiner, G. J.; Wom, H. (1967). "The Defibrination Syndrome: Clinical Features and Laboratory Diagnosis". Department of Medicine and the American National Red Cross Research Laboratory: 528. doi:10.1111/j.1365-2141.1967.tb00762.x. Retrieved 10/02/13. Check date values in: |accessdate= (help) Fibrin is a non-globular protein involved in the clotting of blood.