Diffuse panbronchiolitis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Laboratory Findings
These include: chronic bronchial and bronchiolar inflammation, lung tissue lesions, proliferation of lymphocytes (white blood cells that fight infection), neutrophil granulocytes (white blood cells involved with inflammation) and foamy histiocytes (tissue macrophages) in the lung lumen;[1] [2] detectable haemophilus influenzae (an opportunistic bacterium),[1] pseudomonas aeruginosa (another opportunistic bacterium) and pus in the sputum (coughed-up phlegm);[3][2] chronic sinusitis (inflamed paranasal sinuses),[4][5] hypoxemia (low levels of oxygen in the blood),[6] nodules within terminal and respiratory bronchioles in both lungs,[7][8] dyspnea (shortness of breath),[9][5] elevated IgG and IgA (classes of immunoglobulins),[10] occurrences of elevated rheumatoid factor (an indicator of autoimmunity),[10] and hemagglutination (clumping of antibodies in the blood).[10][11]
References
- ↑ 1.0 1.1 Poletti V, Casoni G, Chilosi M, Zompatori M (2006). "Diffuse panbronchiolitis". Eur Respir J. 28 (4): 862–871. PMID 17012632.
- ↑ 2.0 2.1 Yanagihara K, Kadoto J, Kohno S (2001). "Diffuse panbronchiolitis--pathophysiology and treatment mechanisms". Int J Antimicrob Agents. 18 (Suppl. 1): S83–87. PMID 11574201.
- ↑ Homma H, Yamanaka A, Tanimoto S, Tamura M, Chijimatsu Y, Kira S, Izumi T (1983). "Diffuse panbronchiolitis. A disease of the transitional zone of the lung". Chest. 83 (1): 63–69. PMID 6848335.
- ↑ Martinez JA, Guimaraes SM, Ferreira RG, Pereira CA (2000). "Diffuse panbronchiolitis in Latin America". Am J Med Sci. 319 (3): 183–185. PMID 10746829.
- ↑ 5.0 5.1 Fitzgerald JE, King TE Jr., Lynch DA, Tuder RM, Schwarz MI (1996). "Diffuse panbronchiolitis in the United States". Am J Respir Crit Care Med. 154 (2 pt. 1): 497–503. PMID 8756828.
- ↑ Chu YC, Yeh SZ, Chen CL, Chen CY, Chang CY, Chiang CD (1992). "Diffuse panbronchiolitis: report of a case". J Formos Med Assoc. 91 (9): 912–915. PMID 1363394.
- ↑ Chantarotorn S, Palwatwichai A, Vattanathum A, Tantamacharik D (1999). "Diffuse panbronchiolitis, the first case reports in Thailand". J Med Assoc Thai. 82 (8): 833–838. PMID 10511794.
- ↑ Sandrini A, Balter MS, Chapman KR (2003). "Diffuse panbronchiolitis in a Caucasian man in Canada". Can Respir J. 10 (8): 449–451. PMID 14679410.
- ↑ Chen Y, Kang J, Li S (2005). "Diffuse panbronchiolitis in China". Respirology. 10 (1): 70–75. PMID 15691241.
- ↑ 10.0 10.1 10.2 Tsang KW, Ooi CG, Ip MS, Lam WK, Ngan H, Chan EY, Hawkins B, Ho CS, Amitani R, Tanaka E, Inoh H (1998). "Clinical profiles of Chinese patients with diffuse panbronchiolitis". Thorax. 53 (4): 274–280. PMID 9741370.
- ↑ Schulte W, Szrepka A, Bauer PC, Guzman J, Costabel U (1999). "Diffuse panbronchiolitis. A differential diagnosis of chronic obstructive lung disease". Dtsch Med Wochenschr. 124 (19): 584–588. PMID 10365176.