Dopamine antagonist
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
A dopamine antagonist is a drug which blocks dopamine receptors (of which there are five types in the human body; they are found in the brain, peripheral nervous system, blood vessels, and the kidney).
Uses and examples
- Used as atypical antipsychotics (coupled with a serotonin antagonist): clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole
- Used as antiemetics: metoclopramide, droperidol, domperidone
- Used as tricyclic antidepressants: amoxapine
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