Drostanolone propionate

Drostanolone propionate

Clinical data
Pregnancy category	X
Routes of administration	Intramuscular injection or transdermal cream
ATC code	A14
Legal status
Legal status	CA: Schedule IV US: Schedule III
Pharmacokinetic data
Bioavailability	Oral 0-2%, Intramuscular 100%
Protein binding	highly
Metabolism	hepatic
Elimination half-life	?
Excretion	renal
Identifiers
IUPAC name (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9, 11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
CAS Number	58-19-5
PubChem CID	6011
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C23H36O3
Molar mass	360.53 g/mol
3D model (JSmol)	Interactive image
SMILES CCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@H](C(=O)C4)C)C)C

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Drostanolone (trade name Masteron) is an anabolic/androgenic steroid. It is known to be highly androgenic and mildly anabolic. It is incapable of aromatization and has similar properties to dihydrotestosterone. It has been successfully used as a breast cancer drug but because of the high risk of virilization safer options are prescribed.

Use in sports

Masteron is used primarily by athletes who need to retain strength while losing mass. It is beneficial to runners and athletes who must remain in a certain weight class. It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug.

References

• Eur J Cancer Clin Oncol. 1983 Sep;19(9):1231-7.
• Cancer Res. 1982 Nov;42(11):4408-12 Marin P, Oden B, and Bjorntorp P. Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: effects of androgens. J Clin Endocrinol Metab 80: 239-243, 1995
• Sem Hop. 1982 Sep 23;58(34):1919-23.

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