Dysplastic nevus laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
There are no laboratory findings associated with the diagnosis of melanoma. Serum lactate dehydrogenase (LDH) may be elevated among patients with metastasis.
Laboratory Findings
- There are no laboratory findings associated with the diagnosis of melanoma. Measurement of serum LDH may be considered for follow-up among patients who have been diagnosed with stage IB-IV melanoma.[1]
Lactate Dehydrogenase (LDH)
- Once metastatic melanoma is diagnosed, serum lactate dehydrogenase (LDH) may be helpful for follow-up.[1]
- For patients with stage IB-IV melanoma, measurement of serum LDH may be considered every 6-12 months.[1]
Diagnosis
The following algorithm illustrates the approach to patients with suspected melanoma.[1]
Suspicious pigmented lesion | |||||||||||||||||||||||||||||||||||||||||||||||
Biopsy | |||||||||||||||||||||||||||||||||||||||||||||||
Inadequate | |||||||||||||||||||||||||||||||||||||||||||||||
Rebiopsy | |||||||||||||||||||||||||||||||||||||||||||||||
Melanoma confirmed | |||||||||||||||||||||||||||||||||||||||||||||||
Breslow thickness | Ulceration status | Mitotic rate | Depth and peripheral margin status | Presence of satellitosis | Clark level for lesions ≤ 1 mm | ||||||||||||||||||||||||||||||||||||||||||
Reassessment with complete physical examination, including neurological exam and lymph node assessment | |||||||||||||||||||||||||||||||||||||||||||||||