Endomyometritis

Endomyometritis Treatment Early Infection:1st 48 hours after delivery ▸ Cefoxitin 2 gm IV q6–8h OR ▸ Ticarcillin-Clavulanate 3.1 gm IV q4–6h OR ▸ DoripenemNAI 500 mg IV q8h OR ▸ Imipenem 0.5 gm IV q6h OR ▸ Meropenem 1 gm IV q8h OR ▸ Ampicillin-Sulbactam 3 gm IV q6h OR ▸ Ertapenem 1 gm IV q24h' OR ▸ Pipracillin-Tazobactam 4.5 gm IV q6h (or 4-hr infusion of 3.375 gm q8h) PLUS ▸ Doxycycline 100 mg IV/po q12h OR ▸ Clindamycin 450–900 mg IV q8h PLUS ▸ Ceftriaxone 2 gm IV q24h OR ▸ Gentamicin MDD: 2 mg per kg load, then 1.7 mg per kg q8h or OD: 5.1 (7 if critically ill) mg per kg q24h Late Infection:48 hours to 6 weeks after delivery ▸ Doxycycline 100 mg IV/po q12h x 14 days