Eosinophilic pneumonia diagnostic study of choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
Bronchoalveolar lavage (BAL) is the diagnostic study of choice for eosinophilic pneumonia.
Diagnostic Study of Choice
Bronchoscopy with bronchoalveolar lavage
- Bronchoalveolar lavage (BAL) is performed in the majority of patients to exclude infection, hemorrhage, or malignancy.[1]
- The BAL is performed using a sequential instillation and recovery of 50 to 60 mL aliquots in an area of radiographic opacity.
- In acute pneumonia, the BAL fluid typically shows a very high proportion (>25 percent) and total number of eosinophils.[2]
- The median BAL cellularity was 350,000/mm3. BAL eosinophilia was present in all cases with a median of 38%.
- The proportion of BAL lymphocytes is approximately 10 to 30 percent and the proportion of BAL neutrophils is 1 to 16 percent.
- The level of eosinophilia returns to normal when the illness resolves.
References
- ↑ Hayakawa H, Sato A, Toyoshima M, Imokawa S, Taniguchi M (1994). "A clinical study of idiopathic eosinophilic pneumonia". Chest. 105 (5): 1462–6. PMID 8181338.
- ↑ Ogawa H, Fujimura M, Matsuda T, Nakamura H, Kumabashiri I, Kitagawa S (1993). "Transient wheeze. Eosinophilic bronchobronchiolitis in acute eosinophilic pneumonia". Chest. 104 (2): 493–6. PMID 8339639.